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Education

Swansea Uni to deliver advanced therapies

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A significant opportunity: University a centre for cell and gene therapies

SWANSEA U​NIVERSITY’S​ Medical School, through its partnership with Abertawe Bro Morgannwg University Health Board, is to be one of the centres to deliver advanced medical therapies to Wales, which is part of a major investment announced by Welsh Blood Services.

A recently formed health consortium, jointly led by the Welsh Blood Service (on behalf of NHS Wales) and the National Institute for Health Research Birmingham Biomedical Research Centre, has been awarded £7.3M of UK Government funding to ensure more patients benefit from a new generation of breakthrough therapies.

£1.5M will come directly to NHS Wales and £550K to Trakcel, a Welsh software company developing scheduling/tracking software for advanced therapies which is based upon technology developed at Swansea University.

The funding will support the Welsh Government’s commitment to developing an Advanced Therapies Strategy which will enable these therapies to be brought to Welsh patients and Advanced Therapy Medicinal Product (ATMP) companies to reach the clinical market, whilst building expertise, capability and capacity across NHS Wales to benefit patient outcomes.

Speaking of the award, Frank Atherton, Chief Medical Officer for Wales, said: “We welcome the announcement of the successful partnership between Birmingham, Nottingham and Wales NHS centres in bidding for Innovate UK monies. The project is aligned with our ambition to support the development, availability and adoption of new innovative therapies for patients in Wales. Cell- and gene-based advanced therapies offer exciting opportunities, not only for the way we treat people with previously incurable conditions, but also how we work together with industry and NHS Wales in bringing these treatments from bench to bedside.”

The NHS Wales role in the MW-ATTC consortium was led by the Welsh Blood Service, with support from Abertawe Bro Morgannwg and Cardiff & Vale University Health Boards along with the Life Sciences Hub Wales Special Interest Group on Cell and Gene Therapy, which brings together expertise from the Welsh NHS, Universities and industry in the Life Science sector.

As part of the contract award, one of the first advanced therapy treatment sites in Wales will be established within Abertawe Bro Morgannwg at the Joint Clinical Research Facility (JCRF) at Swansea University’s Medical School. The focus of the centre will be to develop the infrastructure, processes and skilled workforce required to enable patients to be cared for, from diagnosis through to post-treatment follow up.

Cath O’Brien, Director of the Welsh Blood Service and MW-ATTC Co-Director, said: “A significant opportunity exists to position Wales as a leader in clinical trial and routine delivery of cell and gene therapies to maximise Welsh patient benefit and opportunities for the national economy. The Welsh Government is committed to exploring these revolutionary developments in healthcare and we are excited to have worked alongside our consortium partners to secure funding through what was a highly competitive tendering process.”

One of the first products that will pass through the Welsh centres is that being developed by one of the consortium partners, Rexgenero and is intended to prevent the need for diabetes-related lower limb amputations for some no option patients. The incidence of diabetes is continuing to increase in Wales and already accounts for ~10% of the NHS Wales budget (£500M) with 200, 000 sufferers today rising to an estimated 500,000 by 2025. Currently around 2000 patients in Wales have non-healing lower limb ulcers that result in approximately 330 amputations per year.

The Midlands & Wales Advanced Therapy Treatment Centre (MW-ATTC) will identify barriers, challenges and solutions to facilitate future deployment and adoption of these transformative therapies within the UK healthcare system.

Advanced treatments, such as cell and gene therapies, show great promise for patients with chronic and terminal conditions that currently cannot be cured. Unlike conventional medicines, these new approaches often aim to selectively remove, repair, replace, regenerate and re-engineer a patient’s own genes, cells and tissues to restore normal function. The project will include potential treatments for arthritis, liver disease, several types of cancer, and diabetic ulcers.

Education

Pembrokeshire school smashes the national grade average

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PUPILS at Castle School were thrilled to collect their exam results this week and discover that between them they had amassed an impressive set of passes.  In contrast to the national average which showed a drop of 1%, students improved on their already impressive average of 90%, collectively gaining 94% passes at grades A* – C.  

Many of the students in year 10 were encouraged to sit some exams early in those subjects they had been prepared for and were similarly rewarded, with their results reflecting the school’s overall average.  

The school’s head, Su Cowell, told us ‘these results are even more remarkable when you compare us with the national average of 61% and take into consideration that we are a non-selective school.  The pupils are to be congratulated on their impressive results. They worked extremely hard and all their revision and efforts have been rewarded. Credit must also go to our staff, of course, who worked tirelessly to ensure that every pupil has the best chance of not only passing but also securing the best grade they are capable of. ‘

Whilst all the pupils are to be congratulated, particular mention should go to Lucy Mansfield who has now amassed an incredible total of 14 GCSEs, with 11 A*s, 2 As and an even more impressive 100% in her Additional Maths exam which included A level material.  Teachers were also delighted that two-thirds of their scientists gained either A or A* in all three subjects, as did the class taking Latin. The school’s director, Harriet Harrison, added, ‘I am delighted to see that despite being non-selective we strive to fulfil each child’s potential and about half of our students take nine or more subjects at GCSE with some of them studying 11, 12, even 14, and still manage to get such impressive results.  In addition several of our students enrolled on an accelerated programme in maths, having already earned the top grade last year. It was fantastic to see that they all gained Distinction in the tougher Additional Maths GCSE with one of them getting full marks, which is incredible.’

As the school reaches its 10th anniversary next year, it has many plans to celebrate and hopes that one of those reasons will include another record-breaking set of results.

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Education

WG invests £7.2m in STEM education

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Astronaut Tim Peake: Promoting STEM study

PRINCE’S TRUST Ambassador Tim Peake landed in Cardiff on Tuesday (Jul 17) to help the Minister for Welsh Language and Lifelong Learning, Eluned Morgan, announce £7.2m of funding to encourage young people, especially girls, to study Science, Technology, Engineering and Maths (STEM) subjects at school.

The astronaut, joined the Minister at an event organised by The Prince’s Trust Cymru at Tramshed Tech where they met young people involved in the youth charity’s STEM-related programmes, There, the Minister announced an investment of £7.2m, including £5.2m of European Union funding, for two similar projects. Gwynedd Council’s £1.9m STEM Gogledd and Swansea University’s £5.3m Technocamps 2 have been awarded £1.4m and £3.8m of EU funding, respectively.

Both projects will help to ensure young people, particularly girls and young women, continue STEM studies at GCSE and beyond with the aim of pursuing STEM-related careers.

Over the next four years, STEM Gogledd will work with 600 young people, 60% of whom will be female, to enrich and promote STEM subjects through a range of activities that complement the mainstream curriculum within schools across Gwynedd, Anglesey and Conwy.

Technocamps 2 will work with 3,600 young people across West Wales, North Wales and the South Wales Valleys, two-thirds of whom will be female. It will target secondary schools which do not currently offer computer science as an option at GCSE, or where the subject is only recently available. The project will enable pupils in these schools to take part in workshops to build on their existing knowledge and enthusiasm for IT and computing.

Announcing the funding, the Minister said: “It is a pleasure to be standing alongside Tim Peake today to announce such an important investment which will help to build the skills of our young people to help drive a the Welsh economy.

“Wales must become a STEM nation if we are to build a modern, dynamic, open economy that benefits everyone in Wales. Both the pace and nature of technological change is increasing dramatically and, to have the skilled workforce to capitalise on it, it is vital we have more young people who choose to study STEM subjects to a sufficiently high standard. While this is quite a challenge to address for both boys and girls, the challenge for girls is much greater.

“This is why I am grateful to organisations like The Prince’s Trust for their pioneering programmes and to role models, like Tim, who are influential in promoting the study of STEM subjects. Tim’s Principia mission inspired a generation and showed just how far, literally, science can take you.

“We cannot just rely on people like Tim, though. We must all play our part in stimulating interest in these crucial subjects as a way of securing the next generation of STEM professionals in Wales. This is why I am so pleased to announce this £7.2m investment, £5.2m of it from the EU, for STEM Gogledd and Technocamps. This is a great example of EU funds helping to enthuse and excite young people, particularly girls, about the opportunities available to them.”

Philip Jones, Director of The Prince’s Trust Cymru said: “We are delighted that Tim Peake was able to join us and Welsh Government in promoting the importance of STEM to Welsh Education today. At The Prince’s Trust Cymru, we believe every young person should have the chance to succeed, and we believe Welsh Government’s latest commitment to STEM activities will help transform more young lives in Wales.”

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Education

Williams marks end of school year

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Proud of reforms: Kirsty Williams

AT THE end of school year, Education Secretary Kirsty Williams has set out what has been achieved through Wales’ national mission for education and what these changes mean for pupils, teachers and parents.

Last September, the Education Secretary announced a national mission to raise standards, reduce the attainment gap, and deliver an education system that is a source of national pride and public confidence.

At a conference held in Cardiff today, the Education Secretary explained how major changes to what pupils are taught, how they are taught and how their teachers are trained and developed are helping to transform schools as we know them.

One of the most significant and wide-reaching of these changes is the new curriculum to be rolled out from 2022. Over 200 pioneer schools across Wales are involved in developing six different Areas of Learning and Experience. This work includes embedding digital competence into all areas of teaching and learning and supporting teachers to develop the new curriculum.

A new independent report published today found that these schools strongly support the changes being made and are enthusiastic about their part in developing Wales’ new curriculum.

Teachers’ professional learning and development has been similarly instrumental to the national mission for education, with this school year seeing:

New professional standards for Teaching and Leadership developed with the profession, for the profession;

The establishment of a new National Academy for Educational Leadership to support all leaders in education at all stages of their careers;

New accredited Initial Teacher Education programmes to be delivered in the academic year 2019/20;

Plans for a new part-time PGCE and Employment Based Route into teaching from 2019/20.

Teachers and pupils will also soon begin to see the benefits of a £36 million fund to reduce infant class sizes, with the appointment of over 80 new teachers across Wales and a capital fund to build new classrooms.

Reducing unnecessary bureaucracy for teachers continues to remain a priority, with this year seeing a £1.2 million investment in the appointment of school business managers – helping headteachers to manage their workload and focus on raising standards and school improvement.

Kirsty Williams said: “When I announced our national mission for education last September I said that we would never be able to achieve our ambitions if we just stayed still.

“That’s why the past year has been all about momentum – a drive for self-improvement that reaches right across our education system.

“We still have much work to do but I’m proud of the reforms that we have introduced in a relatively short space of time. I am also genuinely impressed by how everyone in the education system has responded.

“When I visit schools and talk to teachers and pupils, I am always struck about what they’re achieving and how they are improving – whether that’s in developing the new curriculum or discovering new ways of teaching and learning.

“In return, we are introducing the most comprehensive changes to teacher training and development in years, ensuring that our teaching profession are fully prepared and equipped when they start to teach our new curriculum.

“Our schools are changing, education in Wales is changing and I’m confident that our national mission is well on course to deliver the wholesale reforms that we need.”

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