News
Substitution in psychoactive substances a growing concern for experts

THERE is evidence of a growing market in the manufacture and distribution of new benzodiazepine susbstances, with 71% of samples of what users think is diazepam testing positive for other chemicals.
Street valium is bought and sold on the streets of Wales for as little as 50p per tablet.
Josie Smith, Head of Substance Misuse for Public Health Wales and Programme Lead for WEDINOS said: “Although there are always concerns and potential for adverse effects from the consumption of psychoactive substances, the risk is increased by the rising prevalence of substance substitution within the unregulated illicit benzodiazepine market.
“As substitute substances have varying therapeutic doses and duration of effects, there is a concern in relation to the increased potential for an individual to experience adverse and acute effects; including accidental overdose, hospitalisation and death.”
Public Health Wales’s WEDINOS service has seen an increase in the number of samples submitted for testing in the last year, with the substitution of substances within drug groups a key emerging trend.
The WEDINOS Annual Report for 2018-19 also identifies a substantial increase in non-prescribed ‘prescription’ medications being submitted to its drug testing facility.
As in 2017/18, benzodiazepines were the most commonly identified class of psychoactive substances.
Benzodiazepines such as Diazepam, Etizolam and Alprazolam (Xanax) are common sedative drugs often prescribed for anxiety and insomnia.
In addition to prescribed medical use, benzodiazepines are used recreationally and there is evidence of a growing market in the manufacture and distribution of new benzodiazepine substances.
This year, WEDINOS found a higher frequency of substitution amongst samples submitted as benzodiazepines, in particular, diazepam; with nearly three quarters of all samples submitted as diazepam in the first quarter of 2019 were found to contain other substances.
For the first time this year, WEDINOS tested samples of benzodiazepines submitted in blister pack form that contained a substance different to that named on the pack.
Josie Smith continues: “The evidence of substitution indicates that even if a person has purchased tablets looking like a medication, they may not contain the stated contents. This represents a public health challenge and a need for greater awareness and pragmatic harm reduction advice and education.”
The report shows a 58 per cent increase in the number of samples submitted to WEDINOS for testing in 2018-19 compared to the previous year. In total, 2,145 samples were tested between April 2018 and March 2019.
Public Health Wales produces reports and information to influence national and international policy to ensure it is based on the best evidence to protect and improve health.
Those seeking to receive support for drug or alcohol related concerns can contact the Wales Drug and Alcohol Helpline on freephone 0808 808 2234, by texting DAN to: 81066 or by visiting dan247.org.uk
Business
Haverfordwest opticians celebrate 100 years of long service

WALES’ LARGEST Specsavers store is celebrating a series of individual long service milestones, with nine team members collectively marking a century of long service in 2025.
At the heart of the celebrations is Andy Britton, ophthalmic director at Specsavers Haverfordwest, who has worked at the company for 20 years.
Since becoming a partner in 2006, Mr Britton has overseen the store’s transformation from a small site with just four test rooms to a state-of-the-art £1.2 million premises at 21 Riverside Quay. The enhanced store now boasts 14 test rooms equipped with cutting edge technology and a significantly larger team, growing from 11 to 45 employees.
Haverfordwest residents benefit from Mr Britton’s clinical expertise – he holds multiple postgraduate diplomas that allow him to prescribe medication directly to customers, helping to ease pressure on local GP surgeries and hospitals. He has also led the introduction of enhanced services, including glaucoma monitoring, ensuring more people can access specialist care closer to home.
Reflecting on his career, Mr Britton says: ‘It’s been a privilege to serve the Haverfordwest community over the last 20 years. I’m proud of the team we’ve built and the progress we’ve made – all with the aim of delivering the best possible care for our customers.’
Mr Britton’s anniversary was celebrated alongside colleagues Elise Evans, Gareth Riley and Carrie Lewis-Jones – each marking 15 years with Specsavers – as well as other team members celebrating 10 and five-year milestones.
Fellow director, Wayne Jones, was among those celebrating five years with the business, after joining the Haverfordwest store in 2020. He was named a finalist for Optometrist of the Year at the Optometry Wales Awards in 2023 and then in 2024, joined forces with Mr Britton as retail director of the store.
Commenting on the milestone, Mr Jones says: ‘Our team’s experience and dedication are what makes Specsavers Haverfordwest so special. Reaching 100 years of individual long service milestones in 2025 is something we’re incredibly proud of. It’s a real testament to the commitment of our colleagues, and we look forward to many more successful years ahead.’
To mark the occasion, the directors hosted an in-store awards ceremony, presenting certificates and bottles of champagne to the nine long-serving team members celebrating.
Specsavers Haverfordwest is open seven days a week. To find out more information about Specsavers in Haverfordwest, request an appointment or browse the online store, visit https://www.specsavers.co.uk/stores/haverfordwest.
Additionally, to make eye health accessible to all, the store offers a Home Visits service for those unable to leave their homes unaccompanied due to disability or illness.
Community
Appeal launched as Welsh teenagers missing for nearly a week

POLICE have launched an appeal after two teenagers from Wales went missing almost a week ago.
Isobel and Daniel, both aged 16, were last seen together in the Machynlleth area of Powys on Monday. They are from the Cardigan area of Ceredigion and are believed to have links to both Gloucestershire and Merseyside.
Isobel is described as 5ft 3ins tall with blonde hair. She was last seen wearing a black parka-style coat with a fur-trimmed hood, grey jogging bottoms, and carrying a large black backpack.
Daniel is described as 6ft 1ins tall, with short dark brown hair shaved at the sides. He was last seen wearing dark blue jeans, a black T-shirt, and a black collared coat. He was carrying a large camping backpack in black, red, and grey.
Dyfed-Powys Police is urging anyone with information about their whereabouts to get in touch via the online portal, by emailing 101@dyfed-powys.police.uk, or by calling 101.
Business
Government-backed scheme future-proofs Flintshire firms

Productivity, sustainability and skills boosted through decarbonisation initiative
A GOVERNMENT-funded programme is helping businesses in Flintshire become more productive, sustainable and future-ready through cutting-edge support and innovation.
Delivered by AMRC Cymru, a leading research and development facility based in Broughton and part of the University of Sheffield, the initiative has already supported 32 local companies through a combination of tailored reports, training events and one-to-one assistance.
The scheme—Accelerating Decarbonisation and Productivity Technology and Skills (ADAPTS)—is backed by £811,000 from Flintshire’s share of the UK Government’s Shared Prosperity Fund (UKSPF). It aims to boost growth, reduce carbon emissions and create skilled employment across the county’s manufacturing sector.
Sixteen of the participating businesses also received in-depth support from AMRC Cymru engineers to implement new technologies, enhance workforce skills and address key areas for improvement identified in their initial assessments.
Among those to benefit was Biofortuna, a contract development and manufacturing organisation, which developed an automated solution to scale up a critical process—opening doors to new markets while maintaining high accuracy.
Chris McCarthy, development and manufacturing manager at Biofortuna, said:
“If we hadn’t partnered with AMRC Cymru, we would have had to invest a significant amount of time and resource into researching potential options—and even then, we may have ended up limited to off-the-shelf solutions.
ADAPTS gave us the opportunity to approach our challenge from a completely different angle. They developed bespoke solutions tailored specifically to our needs.”
Natalie Jones, project manager at AMRC Cymru, added:
“Seeing the difference the UKSPF-funded ADAPTS programme has made to Biofortuna’s productivity and precision is fantastic. I’m excited to watch how this new technology supports their ongoing growth.”
Reflecting on the wider impact of the scheme, she continued:
“We’ve achieved excellent results across a number of key performance areas—including adoption of new products and services, improved digital connectivity, increased efficiency, and reduced carbon emissions.
Given the nature and timescale of the work, the full impact of the programme will continue to unfold in the months and years ahead, especially in terms of job creation and retention.”
Councillor Chris Dolphin, Flintshire County Council’s cabinet member for economy, environment and climate, welcomed the scheme’s success:
“With UK manufacturers investing around £38.8 billion into the economy each year, it’s great to see the ADAPTS programme preparing Flintshire businesses for future growth.
I believe this investment will boost local resilience and, in the long term, help attract and retain talent in the county.”
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