News
Pembroke cancer sufferer given major lifeline by international drug company on compassionate grounds
Pembroke cancer sufferer Josh Carter-Hewins has been given a major lifeline following international drug company – Roche Pharmaceutical’s – decision, to grant him the Glofitamab drug on compassionate grounds.
Josh, who suffers from the rare and exceptionally aggressive Burkitt’s Lymphoma, was told by his consultants that he wasn’t eligible for further treatment.
But this week, Roche agreed to grant the Glofitamab drug to the 27-year-old on compassionate grounds.
“It’s absolutely fantastic that we have been heard,” Josh’s wife, Beth, told The Pembrokeshire Herald.
“What Roche has decided to do is exceptionally rare and has come as a huge shock to us all.”
The couple will now be travelling to London where Josh will commence his treatment which is expected to last between five and 12 months.
“Obviously there’s no guarantee that this drug will work, but this is our best hope,” said Beth.
Josh first began feeling unwell in 2021 when he was diagnosed with ulcerative colitis, which is a chronic inflammatory bowel disease. He later developed chronic liver disease and in 2023, underwent a liver transplant.
He made a good recovery, however earlier this year, he once again began feeling unwell.
“His symptoms were very similar to that of his ulcerative colitis with stomach pain, bloating and a general fatigue so initially, this is what we believed it was,” explained Beth.
But further analyses showed that Josh, who is employed as a CAD technician and account manager for the traffic light company, CORE highways, was suffering from the extremely rare post transplant lymphoma – Burkitt Lymphoma. Three weeks ago he was given a scan that showed his intensive chemotherapy had failed and his cancer was showing up in more places than before. He was also told that the only option available to treat the cancer is CAR-T cell therapy.
“But unfortunately Josh wasn’t eligible because his lymphoma is driven by being immunosuppressed,” said Beth.
“He wasn’t going to accept this, so he did his own extensive research and found the drug – Glofitamab – which has been used to treat a very small number of Burkitt’s Lymphoma cases across Canada, Copenhagen, Sweden and the USA. And all those cases have gone into remission.”
Sold under the brand name Columvi, this bispecific monoclonal antibody is used for the treatment of large B-cell lymphoma. However, because it isn’t licensed for use on Burkitt’s Lymphoma, the drug can only be administered through private hospitals.
“Josh and his consultants have made a huge effort researching, contacting other Burkitt’s Lymphoma survivors all over the world, holding discussions with doctors across the globe, meeting private consultants, holding meetings at the Senedd and more. We’ve also had extensive media coverage and every like, share, message and donation has made such a huge difference. We’ve been totally blown away by the way the community has come together to help us through this very difficult time.”
Meanwhile Josh and Beth are preparing themselves for the next chapter in their fight to combat Burkett’s Lymphoma.
“The gift from Roch doesn’t include the second drug, Polituzmab Vedotin, nor any other treatment which Josh may need, so we may still need to access private treatment along our journey. So all the donations we’ve received will be used to support his treatment and other potential options, if they become available.
“What Roche and NHS England are doing is fantastic, and they’re doing all they can to give Josh a chance.
“But we still want people to spread the word of Josh’s story, and help bring some light to people like him who are suffering from Burkitt’s Lymphoma.”
Community
Crowds line streets as tractor run hailed a festive success
CROWDS lined streets and pavements across Pembrokeshire on Saturday evening (Dec 20) as Clarbeston Road AFC’s illuminated Christmas tractor run was hailed a resounding success.
More than 200 tractors took part in the event, travelling through villages and towns including Newmoat, Maenclochog, Llys-y-frân, Walton East, Clarbeston Road, Wiston, Newbridge, Poyston Cross, Crundale and Haverfordwest, where large crowds gathered to watch the festive convoy pass through.
Families, children and residents wrapped up against the cold to enjoy the sight of tractors decorated with Christmas lights and festive displays, with applause and waves greeting drivers as they made their way through built-up areas and rural roads alike.
The convoy set off from the Clarbeston Road AFC Knock Playing Fields at 5:30pm and concluded at the County Showground in Haverfordwest later in the evening. At the end of the run, refreshments were available and the raffle draw took place at the Park House building, which was open to the public.
Organisers said the turnout from both drivers and spectators exceeded expectations, with the event once again bringing communities together while raising funds for local causes, including The Catrin Vaughan Foundation, In It With Isaac, and Wales Air Ambulance.
Clarbeston Road AFC thanked tractor drivers, volunteers, sponsors and members of the public for their support, as well as residents and road users for their patience while the convoy passed through.
The illuminated tractor run has become a firm fixture in the local festive calendar, with Friday night’s event described by many spectators as one of the best yet.

Community
Charity tractor and car run set to raise funds for Macmillan and Paul Sartori
A CHARITY tractor and car run in memory of Charles Rees is set to take place in Pembrokeshire later this month, with funds raised supporting Macmillan Cancer Support and Paul Sartori Hospice at Home.
The Charles Rees Tractor & Car Run will be held on Sunday, December 28, 2025, starting and finishing at Dudwell Farm in Camrose.
Participants are being invited to “start their engines” in aid of the two charities, with gates opening at 9:00am and the convoy leaving promptly at 10:30am. Organisers have confirmed that the run will operate with no halfway stops, returning to Dudwell Farm at the end of the route.
The event will begin and finish at Dudwell Farm, Camrose (SA62 6HJ), and is open to tractors and cars. Registration and cash payment will take place on the day, with the price to be confirmed nearer the event.
Additional donations can also be made locally in the run-up to the event at Camrose Country Hardware and Croesgoch Stores.
The run has been organised to raise money for Macmillan Cancer Support, which provides vital care and assistance to people living with cancer, and Paul Sartori Hospice at Home, which supports patients and families across Pembrokeshire during some of the most difficult times of their lives.
Organisers say more information will be released closer to the event and are encouraging the local community to support the run, whether by taking part, donating, or lining the route to show support.
The event is expected to attract strong local interest, continuing Pembrokeshire’s tradition of community-led fundraising in support of much-valued charities.

News
Late Griffiths strike caps dramatic Clarby fightback in nine-goal thriller
CLARBESTON ROAD staged a remarkable comeback to edge out Pennar Robins in a breathless Division One contest that delivered nine goals, wild swings of momentum and a hat-trick that ultimately counted for nothing.
Despite falling behind on three separate occasions, Clarby showed resilience and attacking intent to secure a 5–4 victory, sealed late on by Emyr Griffiths after the hosts had earlier trailed 3–1 in the first half.
For Pennar, the result was a bitter one. Jack Jones struck three times and the Robins led at 1–0, 3–1 and 4–3, but each advantage slipped away as Clarby refused to lie down.
The opening exchanges hinted at little of what was to come. Ben ‘Rocky’ John tested Pennar goalkeeper Ryeley Clark early on, while Tom Davies dragged an effort wide at the other end. The game burst into life after nine minutes when Pennar opened the scoring following a slick team move. Nicholas Willis drove forward down the right, combined neatly with Kieran Smith and Noah Davison, and was tripped inside the box. Jack Jones made no mistake from the penalty spot.
Clarby responded almost immediately. Player-manager Matthew Ellis, keen to atone for conceding the penalty, rose to head home Travis Jones’ corner at the near post just two minutes later.
Pennar regained control midway through the half. Tom Grimwood’s curling corner was met by Jones, who nodded in at the back post, and moments later the same duo combined again as Jones completed his hat-trick, finishing from close range after Grimwood beat his marker and cut the ball back.
Crucially, Clarby struck back before the break. Matthew Bowen delivered an inviting cross from the left and John powered a header past Clark to give the hosts renewed belief heading into half-time.
With the wind at their backs, Clarby came out flying after the restart. John levelled matters by cutting inside and firing low into the corner, before sustained pressure saw Matthew Davies have a goal ruled out for offside and substitute Josh Woods flash a shot across goal.
Against the run of play, Pennar edged back in front on 69 minutes when substitutes combined — Adam Phillips delivering a cross that Conner Phillips met unmarked to head home.
Once again, Clarby refused to fold. Jack Ashman drove forward from the edge of the area and thundered a high finish into the net to make it 4–4, before the decisive moment arrived 12 minutes from time. Griffiths broke through the Pennar back line and showed composure to lift the ball beyond Clark, completing a stunning turnaround.
Clarby managed the closing stages well to see out a vital win ahead of the Christmas break.
Man of the match: Jack Jones
Despite ending on the losing side, Jones’ clinical finishing and constant threat were impossible to ignore. Kieran Smith and Noah Davison were also influential in Pennar’s first-half dominance, while Ben John was central to Clarby’s revival before limping off with a knee issue.
Clarby player-manager Matthew Ellis said: “It’s a huge three points. After nine goals your head’s spinning a bit, but you’ll take it when you’re on the right side of the result. Pennar caused us problems early on, but we really turned it around after the break.”
Pennar manager Craig Butland said: “The second half wasn’t good enough. Individual errors are hurting us and conceding just before half-time changed the momentum. We’ve got to see games out better.”
Clarbeston Road: Rhys Mansell, Matthew Bowen, Greg Brown, Matthew Griffiths, Samuel Hurton, Jack Ashman, Emyr Griffiths, Matthew Davies (capt), Matthew Ellis, Ben John (Jake Wesley 62), Travis Jones. Sub not used: Joseph Jones.
Pennar Robins: Ryeley Clark, Nick Willis (Ryan Walters 80), Alex Wheeler (Adam Phillips 53), Ethan Ball, Bobby Jones (Conner Willis 53), Connor Roberts, Tom Grimwood, Kieran Smith (capt), Noah Davison, Jack Jones, Toby Davies.
Referee: Stefan Jenkins.
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