News
Pembroke cancer sufferer given major lifeline by international drug company on compassionate grounds
Pembroke cancer sufferer Josh Carter-Hewins has been given a major lifeline following international drug company – Roche Pharmaceutical’s – decision, to grant him the Glofitamab drug on compassionate grounds.
Josh, who suffers from the rare and exceptionally aggressive Burkitt’s Lymphoma, was told by his consultants that he wasn’t eligible for further treatment.
But this week, Roche agreed to grant the Glofitamab drug to the 27-year-old on compassionate grounds.
“It’s absolutely fantastic that we have been heard,” Josh’s wife, Beth, told The Pembrokeshire Herald.
“What Roche has decided to do is exceptionally rare and has come as a huge shock to us all.”
The couple will now be travelling to London where Josh will commence his treatment which is expected to last between five and 12 months.
“Obviously there’s no guarantee that this drug will work, but this is our best hope,” said Beth.
Josh first began feeling unwell in 2021 when he was diagnosed with ulcerative colitis, which is a chronic inflammatory bowel disease. He later developed chronic liver disease and in 2023, underwent a liver transplant.
He made a good recovery, however earlier this year, he once again began feeling unwell.
“His symptoms were very similar to that of his ulcerative colitis with stomach pain, bloating and a general fatigue so initially, this is what we believed it was,” explained Beth.
But further analyses showed that Josh, who is employed as a CAD technician and account manager for the traffic light company, CORE highways, was suffering from the extremely rare post transplant lymphoma – Burkitt Lymphoma. Three weeks ago he was given a scan that showed his intensive chemotherapy had failed and his cancer was showing up in more places than before. He was also told that the only option available to treat the cancer is CAR-T cell therapy.
“But unfortunately Josh wasn’t eligible because his lymphoma is driven by being immunosuppressed,” said Beth.
“He wasn’t going to accept this, so he did his own extensive research and found the drug – Glofitamab – which has been used to treat a very small number of Burkitt’s Lymphoma cases across Canada, Copenhagen, Sweden and the USA. And all those cases have gone into remission.”
Sold under the brand name Columvi, this bispecific monoclonal antibody is used for the treatment of large B-cell lymphoma. However, because it isn’t licensed for use on Burkitt’s Lymphoma, the drug can only be administered through private hospitals.
“Josh and his consultants have made a huge effort researching, contacting other Burkitt’s Lymphoma survivors all over the world, holding discussions with doctors across the globe, meeting private consultants, holding meetings at the Senedd and more. We’ve also had extensive media coverage and every like, share, message and donation has made such a huge difference. We’ve been totally blown away by the way the community has come together to help us through this very difficult time.”
Meanwhile Josh and Beth are preparing themselves for the next chapter in their fight to combat Burkett’s Lymphoma.
“The gift from Roch doesn’t include the second drug, Polituzmab Vedotin, nor any other treatment which Josh may need, so we may still need to access private treatment along our journey. So all the donations we’ve received will be used to support his treatment and other potential options, if they become available.
“What Roche and NHS England are doing is fantastic, and they’re doing all they can to give Josh a chance.
“But we still want people to spread the word of Josh’s story, and help bring some light to people like him who are suffering from Burkitt’s Lymphoma.”
News
Two local musicians awarded four-figure bursaries from Menter Rhosygilwen
Two leading musicians are to receive funding totalling £8,000 thanks to a new music bursary launched by Menter Rhosygilwen.
Cardigan pianist Raph James and Pembrokeshire trumpeter Carys Wood are both to receive £4,000 of funding spread over the next two years, after receiving offers to continue their performance studies at two of the UK’s top music colleges.
Raph, who is taught by Pembrokeshire-based pianist Sarahjane Absalom, has been accepted by both the Guildhall School of Music, London and the Royal Northern College of Music, Manchester, while Carys has been accepted by both the Royal College of Music and the Royal Academy of Music, London.
“This is the first year that we’ve launched the bursary, and its aim is for young people in Dyfed who have been accepted to study at a music academy,” explained Glen Peters, owner and director of Menter Rhosygilwen.
“This year the standard was so high that we were compelled to award it to two students rather than one, and as a result we’ve increased the bursary from £6,000 to £8,000.”
Raph, who recently gained his Associate of the Royal Schools of Music performance diploma with an exceptionally high score, is also the current Young Musician of Dyfed after wowing judges with his outstanding performance at Rhosygilwen in 2024. He is a Year 13 student at Cardigan Secondary School where he is currently preparing for A levels in maths, physics, and chemistry. He will commence his performance studies at the Guildhall School of Music in September.
Carys Wood is a sixth form student at Haverfordwest High School. In 2024 she reached the last 50 televised rounds of the BBC Young Musician and in September she will commence her undergraduate studies at the Royal Academy of Music in London.
Raph and Carys will officially receive their bursaries at a special awards ceremony at Rhosygilwen in April.
Community
Grieving family’s aim to protect young drivers in memory of daughter
PEMBROKESHIRE COUNTY COUNCIL Road Safety Team have worked in partnership with the family of a young woman killed in a road traffic collision to launch an intervention for young drivers in our County and beyond.
Ella Bee’s Story aims to prevent further deaths on the road, particularly among the 17 to 25-year-old age group, and concentrates on the Fatal 5, peer pressure, driver behaviour and how to reduce the risks both as a driver and passenger.
Twenty-one year-old Ella Smith was killed in a road traffic collision on the Broad Haven road in 2021 and her family are bravely telling their story of the night it happened and the aftermath of losing Ella.
Two drivers involved in the collision were jailed for ten years each having been convicted of causing death by dangerous driving and causing serious injury by dangerous driving.
The intervention was launched recently and will be available to all schools and young peoples’ groups in the County, along with Pembrokeshire College.
The Road Safety Team worked closely with the family to put together the intervention which includes the production of two videos that can help educate all young drivers, and any adults with young drivers in the family.
Following the launch Ella’s mother Maria said: “We as a family and Ella’s best friends have worked tirelessly with Pembrokeshire County Council to produce a presentation on road safety to be delivered to schools, colleges and youth groups to educate young drivers on the devastating impact that losing Ella has had on us all.
“Ella your legacy will live on and you will forever be remembered for helping others even now.”
Cabinet Member for Residents’ Services Cllr Rhys Sinnett added: “The launch of Ella Bee’s Story was incredible moving. Ella’s family has been incredibly brave in their determination to ensure her tragic death is not in vain and this project will help other young drivers stay safe on our roads.”
For further information about how your school or youth group can access Ella Bee’s Story please email [email protected]
Community
Storm Éowyn upgraded to ‘danger to life’ amber warning for Wales
THE MET OFFICE has upgraded its weather alert for Storm Éowyn to an amber warning, signifying a “danger to life” as strong winds and heavy rain approach Wales and other parts of the UK. The warning is in effect from 6:00am to 9:00pm on Friday, covering northern Wales, Northern Ireland, northern England, and southern Scotland.
Strong winds and widespread disruption
The amber alert warns of winds reaching 60-70 mph inland and up to 90 mph in exposed coastal areas and high ground. The Met Office advises that flying debris poses a risk to life, while power cuts, travel disruption, and property damage are highly likely.
Road, rail, air, and ferry services are expected to face delays and cancellations. Homes and businesses may also sustain structural damage as the storm progresses.
Areas in Wales under amber warning:
- Conwy
- Denbighshire
- Flintshire
- Gwynedd
- Isle of Anglesey
Alongside the amber alert, two yellow warnings for wind cover all of Wales on Friday, lasting from midnight Thursday to midnight Friday. A separate yellow warning for rain is also in effect from midnight to 9:00am on Friday, predicting 15-25 mm of rain across much of Wales and 40-60 mm in higher elevations. The heavy rainfall may lead to surface water flooding in some areas.
A Met Office spokesperson said: “Storm Éowyn will move across the northwest of the UK on Friday, clearing northeast by Friday night. This will bring a spell of very strong west to southwesterly winds, with a brief reduction in wind strength as the storm’s centre passes over certain areas. Winds will then increase rapidly before gradually easing later on Friday.”
Residents are urged to secure loose outdoor items, avoid unnecessary travel, and monitor updates as the storm approaches.
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