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Pembroke cancer sufferer given major lifeline by international drug company on compassionate grounds

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Pembroke cancer sufferer Josh Carter-Hewins has been given a major lifeline following international drug company – Roche Pharmaceutical’s – decision, to grant him the Glofitamab drug on compassionate grounds.

Josh, who suffers from the rare and exceptionally aggressive Burkitt’s Lymphoma, was told by his consultants that he wasn’t eligible for further treatment.

But this week, Roche agreed to grant the Glofitamab drug to the 27-year-old on compassionate grounds.

“It’s absolutely fantastic that we have been heard,” Josh’s wife, Beth, told The Pembrokeshire Herald.

“What Roche has decided to do is exceptionally rare and has come as a huge shock to us all.”

The couple will now be travelling to London where Josh will commence his treatment which is expected to last between five and 12 months.

“Obviously there’s no guarantee that this drug will work, but this is our best hope,” said Beth.

Josh first  began feeling unwell in 2021 when he was diagnosed with ulcerative colitis, which is a chronic inflammatory bowel disease.  He later developed chronic liver disease and in 2023, underwent a liver transplant.

He made a good recovery, however earlier this year, he once again began feeling unwell.

“His symptoms were very similar to that of his ulcerative colitis with stomach pain, bloating and a general fatigue so initially, this is what we believed it was,” explained Beth.

But further analyses showed that Josh, who is employed as a CAD technician and account manager for the traffic light company, CORE highways, was suffering from the extremely rare post transplant lymphoma – Burkitt Lymphoma. Three weeks ago he was given a scan that showed his intensive chemotherapy had failed and his cancer was showing up in more places than before.  He was also told that the only option available to treat the cancer is CAR-T cell therapy.

“But unfortunately Josh wasn’t eligible because his lymphoma is driven by being immunosuppressed,” said Beth. 

“He wasn’t going to accept this, so he did his own extensive research and found the drug – Glofitamab – which has been used to treat a very small number of  Burkitt’s Lymphoma cases across Canada, Copenhagen, Sweden and the USA.  And all those cases have gone into remission.”

Sold under the brand name Columvi, this bispecific monoclonal antibody is used for the treatment of large B-cell lymphoma.  However, because it isn’t licensed for use on Burkitt’s Lymphoma, the drug can only be administered through private hospitals.

“Josh and his consultants have made a huge effort researching, contacting other Burkitt’s Lymphoma survivors all over the world, holding discussions with doctors across the globe, meeting private consultants, holding meetings at the Senedd and more.  We’ve also had extensive media coverage and every like, share, message and donation has made such a huge difference.  We’ve been totally blown away by the way the community has come together to help us through this very difficult time.”

Meanwhile Josh and Beth are preparing themselves for the next chapter in their fight to combat Burkett’s Lymphoma.

“The gift from Roch doesn’t include the second drug, Polituzmab Vedotin, nor any other treatment which Josh may need, so we may still need to access private treatment along our journey.  So all the donations we’ve received will be used to support his treatment and other potential options, if they become available.

“What Roche and NHS England are doing is fantastic, and they’re doing all they can to give Josh a chance.

“But we still want people to spread the word of Josh’s story, and help bring some light to people like him who are suffering from Burkitt’s Lymphoma.”

 

Crime

Cocaine deaths spark regional summit across West Wales

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Health, police and support services unite after rising concerns in Pembrokeshire, Ceredigion and Carmarthenshire

COCAINE has been identified in a significant number of drug-related deaths across Pembrokeshire, Ceredigion and Carmarthenshire over the past year.

Frontline teams have also reported rising incidents of violence, aggression and criminal justice involvement among people accessing drug and alcohol support services.

Dyfed-Powys Police data shows cocaine is now the force’s second most seized drug, and remains widely used across a range of settings.

In response, the Dyfed Area Planning Board brought together representatives from health, policing, commissioned services, social services and community organisations for a regional summit aimed at understanding the scale of the problem and agreeing joint action.

Hywel Dda’s Community Drug and Alcohol Team opened the event with an overview of emerging substance use trends. Dyfed-Powys Police then shared enforcement intelligence, while Public Health Wales provided a national perspective on stimulant use.

Clinical specialists also outlined the impact of cocaine use on maternity services, blood-borne virus transmission, exercise culture and the night-time economy.

The summit concluded with harm reduction training and group discussions focused on strengthening prevention, treatment pathways and community support across West Wales.

Steve Reynolds, Dyfed Drug and Alcohol Service manager, said: “DDAS are incredibly encouraged by the success of this cocaine summit. Cocaine-related harms are complex and evolving, and through collaboration and open dialogue we can respond effectively.

“The summit reinforced the importance of reducing stigma, expanding access to support, and ensuring that people who use our services receive compassionate, person-centred care.

“We remain committed to working with partners in developing practical actions that improve outcomes for individuals, families and communities.”

Detective Superintendent Gareth Roberts, of Dyfed-Powys Police, said: “It was a pleasure to host this valuable event at Dyfed-Powys Police.

“As a force, we are committed to working in partnership to improve the health, wellbeing, and safety of our communities as we work hard to reduce the risk of drug-related harm.”

Craig Jones, Hywel Dda Prevention and Population Health Improvement Manager, said: “This summit marks the beginning of a coordinated regional effort to reduce harm, improve outcomes and strengthen support for individuals, families and communities affected by cocaine use.

“Partners will now work together to address availability, risk reduction and access to support.”

Anyone experiencing problems with substance use, or anyone seeking more information about the Community Drug and Alcohol Team, can visit hduhb.nhs.wales/drug-and-alcohol.

 

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Crime

Farm owner in court after 26 dogs removed over welfare concerns

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Council awarded control of animals after magistrates hear claims of unlicensed breeding

A PEMBROKESHIRE farm owner has appeared before Haverfordwest Magistrates’ Court after 26 dogs were removed from her care under animal welfare legislation.

Rachel Roberts, of Penlan Oleu, Puncheston, appeared in court on Friday (May 1) in relation to an application brought under Section 20 of the Animal Welfare Act 2006 following action by Pembrokeshire County Council.

The court heard that 26 dogs had been taken into possession, including spaniels, dachshunds, poodles, chihuahuas and six puppies.

It was alleged in court that Roberts had been breeding and selling dogs without the appropriate licence, and that some animals had not received the correct vaccinations.

Magistrates granted the application, allowing Pembrokeshire County Council to take control of the dogs and make decisions about their future, including rehoming.

Roberts was also ordered to pay £99,463.35 in costs to the council.

RSPCA investigation

An RSPCA investigation was reportedly opened last year after images emerged of horses said to be in poor condition.

The Herald has also been contacted by a concerned member of the public, who provided videos and photographs which they claim show a dead horse concealed beneath wooden pallets.

The source further alleged that a person staying at the property had witnessed a horse being dragged by its neck using a tractor.

These claims have not been independently verified by The Herald.

Wider allegations

The Herald has also been told that other members of the family may have been involved in the sale of dogs from the property, with allegations that animals were later sold outside Pembrokeshire.

The paper understands that Roberts’ daughter, Eliza Roberts, has previously appeared before the courts in connection with dog-related offences.

Roberts, 36, was sentenced to three months in prison and banned from owning animals for seven years after pleading guilty to two counts of possession of a fighting dog and one count of being in charge of a dog dangerously out of control.

The charges followed an incident in Hanwell, near Banbury, on March 26, in which a schnoodle named Winnie was killed by two XL Bully dogs, Kobi and Kardi.

At the sentencing hearing, Roberts was ordered to pay £1,295 compensation, and a destruction order was made for the dogs.

 

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Community

Historic Haverfordwest church launches urgent repair appeal

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A HAVERFORDWEST church which has served the town for more than 150 years has launched an urgent appeal for help with essential building work.

St David and St Patrick’s Catholic Church is seeking to raise £3,000 towards repairs to its ageing roof and building structure.

The church, which dates back to 1872, says the work is needed to protect both the historic building and the community services based there.

The appeal has been launched by Helen Johnson through GoFundMe, with the fundraiser saying the church remains an important place of worship, welcome and support for people from a wide range of backgrounds.

The building was designed by Richard Williams of Carmarthen and has been part of Haverfordwest life for generations.

Alongside its religious role, the parish and volunteers from the St Vincent de Paul Society support local families, elderly residents and vulnerable people facing poverty, loneliness and hardship.

Weekly lunch clubs provide warm meals, friendship and a place for people to meet and socialise.

The appeal says that without urgent financial support, maintaining the church and continuing this community work will become increasingly difficult.

The fundraiser states: “Every donation, no matter how small, will help preserve this historic church and the community support it provides for future generations.”

As of Wednesday (May 20), the appeal had raised £10 towards its £3,000 target.

If you can donate, click HERE.

 

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