Health
Wales to lead rollout of first long-acting HIV prevention jab on the NHS
WALES is set to lead the way in the UK’s battle against HIV, with the NHS preparing to offer a new long-acting injectable drug that can prevent infection with just six doses a year.
The National Institute for Health and Care Excellence (NICE) has issued a positive recommendation for cabotegravir, branded as Apretude, making it the first long-acting pre-exposure prophylaxis (PrEP) option available on the Welsh NHS. The medicine, manufactured at GSK’s facility in Barnard Castle, County Durham, is being hailed as a breakthrough for people at risk of HIV who cannot take daily tablets.

Available in Wales within weeks
Because of differences in how health systems are run, Wales is expected to roll out cabotegravir faster than England. Subject to no appeals, the drug will be made available within two months through Welsh NHS services – a move campaigners say could have a major impact on transmission rates.
The medicine has been shown to be significantly more effective than daily oral PrEP. In two large trials, it reduced new HIV infections by 69% and 90% compared to existing tablets. It was also well-tolerated, with only mild side effects such as temporary injection-site soreness.
A Welsh public health opportunity
The Welsh Government has long committed to the goal of ending new HIV transmissions by 2030, but campaigners say progress has been uneven. According to the UK Health Security Agency’s 2024 data, uptake of PrEP remains lowest among heterosexual women, Black African communities, and young people aged 15–24 – groups where new diagnoses are actually rising.
Richard Angell, OBE, Chief Executive of the Terrence Higgins Trust, said:
“We are not on track to meet the 2030 goal of no new HIV transmissions. There are stark inequalities in who is accessing prevention. We need to ensure that everyone in Wales understands their options and can access one that works for them.”
Juddy Otti, Head of HIV Services at the Africa Advocacy Foundation, added:
“More needs to be done to prevent transmission in communities where inequities persist. This new injectable option provides real choice and could help change that.”
How it works
Apretude is given as two starter injections a month apart, followed by one injection every two months – meaning just six visits a year to stay protected. It works by blocking HIV’s ability to integrate into human immune cells, stopping the virus from establishing infection.
Julie Guest, General Manager at ViiV Healthcare UK, said:
“Making cabotegravir available in Wales is a vital step forward in improving accessibility for people who can’t take daily oral PrEP. It’s an important addition to national efforts to bring down new HIV cases.”
With health boards now preparing to deliver the treatment, Wales could become the first nation in the UK to fully implement long-acting injectable HIV prevention on the NHS — a major milestone in public health and a powerful statement of intent to reach zero new HIV transmissions by 2030.
Health
Paediatricians urge parents in Wales to get children vaccinated against flu this winter
PAEDIATRICIANS are urging parents and carers across Wales to ensure their children receive the flu vaccine, as early-season data shows high rates of flu among babies, children and young people.
The Royal College of Paediatrics and Child Health (RCPCH) has published a new fact sheet for families in Wales, amid concerns that flu is already circulating widely in communities. Clinicians say many people still underestimate the seriousness of flu, wrongly believing it to be little more than a heavy cold.
However, flu can cause severe illness in children and lead to complications such as pneumonia and bronchitis. Each winter, thousands of children across the UK – including those with no underlying health conditions – require hospital care because of flu.
The RCPCH fact sheet aims to provide clear, evidence-based information for families and includes:
• Who is eligible for the flu vaccine
• Where to get vaccinated in Wales
• What to do if an appointment has been missed
• Answers to common questions on safety and effectiveness
The guidance is available now and comes as health services prepare for what is expected to be a challenging winter.
Dr Malcolm Gajraj, RCPCH Officer for Wales, said: “Flu is not something to take lightly. We are already seeing considerable cases of flu among children in Wales, and we know from experience that flu can lead to serious illness and hospital stays. The vaccine is safe, effective and the best way to protect your child. By getting your child vaccinated, you’re helping to keep them well and reduce the spread of flu in our communities.”
Health
Women driven to end pregnancies amid row over £28 drug
A DOCTOR who facilitated abortions for two women with much-wanted pregnancies was not allowed to prescribe a £28 anti-sickness drug due to cost-effectiveness rules in Wales.
The stark warning came as petitioners called on the Welsh Government to place Xonvea, the only licensed medication for severe pregnancy sickness, on the routine prescription list.
Georgina Forbes, a specialist doctor in Gwent, revealed she facilitated terminations for two women who were suffering from hyperemesis gravidarum (HG) in a single week. HG, which affects about 3% of pregnancies, leads to extreme, persistent nausea and vomiting.
“Both pregnancies were very much planned and wanted,” she wrote. “Both had multiple admissions and were on other medical treatments which were not giving adequate relief.
“For the sake of their physical and mental health, they felt their only option was to terminate their much-wanted pregnancies – inevitably having a further impact on their well-being.”
She warned of distress for the patients and staff involved because Xonvea “may well be the medication that provides symptomatic relief but departments are not allowed to prescribe it”.
Dr Forbes, chair of the College of Sexual and Reproductive Healthcare’s Wales committee, noted Xonvea costs £28 for a 10-day supply – “far less than the cost of admission”. She urged Welsh ministers to ensure women are not “left behind compared to other UK nations”.
In 2019, the drug was rejected for routine use by the All-Wales Medicines Strategy Group (AWMSG) – which advises ministers – due to “insufficient” evidence of cost-effectiveness. Scotland reached a similar conclusion while access in England is inconsistent.
But campaigners argue the decision is a false economy. Data submitted to the Senedd’s petitions committee highlighted a two-night hospital admission to rehydrate a woman with severe sickness costs the NHS £850, with ambulance call-outs costing a further £238.
Petitioner Sarah Spooner, from Monmouthshire, argued the “myopic approach” ignores the costs of untreated sickness such as perinatal mental health support.
Ms Spooner, whose pregnancy sickness was so severe she had to have a termination, warned of inequality in access to treatments. She recalled having to travel to an abortion clinic in Bargoed to get medication, a process she described as “immensely difficult”.
While the Welsh Government has insisted health boards have discretion to prescribe the drug “when other treatments… are ineffective”, staff and patients report a different reality.
Ms Spooner’s 947-name petition warned women face a “postcode lottery” for care, with only two Welsh health boards making Xonvea more widely available.
She was contacted by Heather Kosick, a Canadian doctor, who was horrified by her story.
Dr Kosick wrote: “Here in Canada Xonvea, also called Diclectin, is readily available to all pregnant women. In fact, it is considered the first-line agent for nausea and vomiting in pregnancy due to its extensive safety data.”
Ms Spooner volunteers for the Pregnancy Sickness Support charity which pointed out that Xonvea has been prescribed globally for years, with an estimated 30 million women treated.
The charity highlighted that 57% of patients are forced to cycle through three or more ineffective drugs before being offered Xonvea, which 83% of women found effective.
One patient reported being hospitalised seven times during a pregnancy without Xonvea but zero admissions during a subsequent pregnancy when she was prescribed the drug.
About 5% of women with HG end a wanted pregnancy due to the severity of symptoms, according to a 2021 study, which found 52% considered termination.
The study, from the Obstetric Medicine journal, found 25.5% of respondents occasionally experienced suicidal thoughts while 6.6% reported frequent suicidal ideation.
Writing to the petitions committee, Wales’ health secretary Jeremy Miles said the 2019 AWMSG appraisal remains the “most up-to-date and comprehensive evaluation”.
He told the committee health boards can make Xonvea available in certain circumstances, with more than 1,140 prescriptions issued between January and July 2025. He added that the manufacturer was “unable” to provide updated information to support a reappraisal.
Mr Miles wrote: “We must ensure our health service treats all conditions and diseases fairly. Taking an evidence-based approach helps us to do this, whatever the disease, by ensuring resources are targeted at where the evidence indicates people will gain the most benefit.”
During today’s (December 8) meeting, Senedd members paid tribute to women for sharing their “horrendous” experiences before deciding to ask the AWMSG to reconsider its position.
Plaid Cymru’s Caerphilly MS Lindsay Whittle said: “I don’t think you can put a price on young families, young couples who wish to start a family and have undergone such traumatic decisions.”
He stressed: “Cost should simply not be the issue – families are suffering.”

Health
MS steps in after disabled man has endures two-year wait for vital dental treatment
Brother says 51-year-old Robert is “wasting away in agony” while their 80-year-old mother struggles to cope
SAMUEL KURTZ MS has intervened in the case of a Pembroke family who say they have been left “abandoned” by the Welsh NHS, after a severely disabled man waited two years for essential dental treatment.
Mr Kurtz confirmed that his office has been in contact with the family since the end of last week, and that he will raise their concerns with the Welsh Government and Hywel Dda University Health Board at the earliest possible opportunity.

The case centres on 51-year-old Robert, who is disabled, non-verbal and relies entirely on his mother for his day-to-day care. According to the family, Robert has suffered severe dental pain for two years, during which time he has been unable to eat properly and has experienced rapid weight loss.
His brother, Alfie Probert, highlighted the situation in an emotional Facebook post that has been widely shared in Pembrokeshire. Alfie said Robert had once been a healthy sixteen stone but is now “wasting away” while the family waits for specialist treatment.
He also described the strain on their mother, who is eighty, unwell herself and caring for Robert around the clock. “We feel completely abandoned,” he wrote. “This isn’t just a backlog. This is cruelty. This is negligence. This is destroying people’s lives.”
The post has prompted a strong local reaction, with many residents tagging Samuel Kurtz and calling for urgent action.
Mr Kurtz said he shared the public’s concerns and would be seeking answers from ministers and Hywel Dda UHB as to how such a long delay could be allowed to develop for a vulnerable adult.
Hywel Dda University Health Board has been approached for comment.
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