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Welsh breakthrough could transform breast cancer detection

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Simple home urine test being developed at Aberystwyth University with NHS backing

A GROUNDBREAKING new home test for early breast cancer detection is being developed in Wales, with scientists at Aberystwyth University leading research that could transform diagnosis for women across rural communities including Pembrokeshire and Carmarthenshire.

Backed by Welsh Government funding and supported by Hywel Dda University Health Board, the pioneering work aims to deliver a simple urine-based test that could ease pressure on NHS Wales services while improving early detection rates in areas where access to specialist diagnostics remains a challenge.

The prototype test, currently under development, is designed as a lateral flow device—similar to a pregnancy or COVID-19 test—that could detect early biochemical signs of breast cancer from a single urine sample.

Researchers say the innovation could support faster diagnosis, reduce reliance on invasive procedures, and ultimately improve survival rates by identifying the disease at its earliest and most treatable stage.

Breast cancer remains the most commonly diagnosed cancer among women globally and is a leading cause of cancer-related deaths in more than 100 countries. While mammograms, MRI scans and biopsies are essential tools, there is growing demand for simpler, more accessible methods of detection.

Rural impact significant

For patients in West Wales, where travel to major hospitals can be time-consuming and access to specialist services limited, the development could prove particularly significant.

A reliable home testing kit could reduce the need for repeated hospital visits and help identify cases earlier, easing pressure on already stretched NHS diagnostic services.

The Herald understands that improved early detection could also play a role in reducing waiting times across NHS Wales, where diagnostic backlogs remain a persistent concern.

Welsh research leading the way

The study at Aberystwyth University is focusing on identifying metabolic changes linked to breast cancer that are excreted in urine, enabling earlier and less invasive detection.

Professor Luis Mur, who is leading the research, said: “Our work is revealing a distinct biochemical ‘signature’ associated with the earliest stages of breast cancer—one that can be detected in a simple urine sample.

“By translating these findings into a lateral flow test, we hope to create a diagnostic tool that is affordable, easy to use at home, and capable of detecting cancer earlier than many current methods.

“Early diagnosis saves lives, and our aim is to make that crucial first step accessible to as many women as possible.”

Professor Mur and breast cancer study manager Dr Aimi Zainurin are working closely with NHS colleagues to ensure the research can move quickly from laboratory discovery to real-world clinical use.

This approach is designed to shorten the time it takes for new medical innovations to reach patients—currently estimated at around 17 years.

Backed by Welsh Government

The project is supported through the Welsh Government’s SMART Award programme, which aims to accelerate innovation and strengthen collaboration between academia and industry in Wales.

It is also co-sponsored by Dynamic Extractions Ltd, whose expertise in separation technologies supports the development of the diagnostic tool.

Dr Helen Munro, National Clinical Lead for Women’s Health based at Hywel Dda University Health Board, said: “This funding has the potential to significantly shorten the time it takes for vital women’s health research to reach real-world clinical practice.

“We’re working closely with our academic partners and health boards to close that gap and ensure innovations—such as the work underway at Aberystwyth University—benefit patients far more quickly.”

Wider women’s health benefits

Alongside breast cancer, the research team is also exploring urine-based diagnostics for conditions including endometriosis and polycystic ovary syndrome (PCOS), both of which are often under-diagnosed.

Scientists hope the wider programme could help tackle long-standing delays in women’s healthcare by providing faster, more accessible diagnostic tools.

If successful, the Welsh-led innovation could place the country at the forefront of a new generation of non-invasive cancer screening—offering hope to thousands of women across Wales and beyond.

Caption:

Top team: Professor Luis Mur and Dr Aimi Zainurin, Aberystwyth University

 

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Who is Andy Burnham, the Prime Minister-in-waiting?

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The Greater Manchester mayor has spent years outside Westminster, but Starmer’s resignation has placed him on the brink of Number 10

ANDY BURNHAM has spent years being described as Labour’s future. Today, that future appears to have arrived.

Following Sir Keir Starmer’s resignation announcement, the Mayor of Greater Manchester is now widely regarded as the overwhelming favourite to become Labour leader and Britain’s next Prime Minister.

For many people outside politics, Burnham is best known as the outspoken mayor who challenged Boris Johnson’s government during the COVID-19 pandemic. But his political career stretches back more than twenty years and includes some of the most senior jobs in government.

Born in Merseyside in 1970, Burnham grew up in a working-class family and has always remained closely associated with his northern roots. A lifelong Everton supporter, he has often spoken about the importance of community, public services and opportunity for ordinary families.

After studying English at Cambridge University, he worked briefly in journalism before entering politics. He was elected Labour MP for Leigh in Greater Manchester in 2001 and quickly became one of the party’s rising figures.

Under Tony Blair and Gordon Brown, Burnham climbed the ministerial ladder. He served as Chief Secretary to the Treasury, Culture Secretary and later Health Secretary, giving him experience across some of the most important departments in government.

His first bid for the Labour leadership came in 2010, after Labour’s general election defeat. He lost to Ed Miliband, but the campaign raised his profile significantly. Five years later, he ran again, only to be defeated by Jeremy Corbyn in the contest that transformed Labour politics.

Rather than remain on the Westminster backbenches, Burnham made a bold move in 2017 by standing for the newly created role of Mayor of Greater Manchester. He won comfortably and went on to become one of the most recognisable regional politicians in Britain.

His national profile grew sharply during the pandemic, when he publicly challenged the UK Government over restrictions and financial support for northern cities. His confrontation with Downing Street won him praise from voters who felt their communities were being ignored by Westminster.

Supporters say Burnham’s appeal lies in his ability to connect with traditional Labour voters while remaining acceptable to the party’s centre ground. They see him as authentic, approachable and more in touch with everyday concerns than many Westminster politicians.

Politically, Burnham has championed greater devolution, arguing that power should be moved away from London to regions and nations across the UK. He has also backed transport reform, stronger public services and economic policies aimed at spreading growth beyond the South East of England.

For Wales, a Burnham premiership would be watched closely. He would inherit a Labour Party still reeling from its collapse in the Senedd election, where Plaid Cymru emerged as the dominant force in Welsh politics.

His emphasis on devolution may be welcomed in Wales, but he would face immediate pressure to show that any new relationship with the nations of the UK is more than rhetoric.

Critics argue that Burnham can be short on detail and long on broad messages. Others point out that he has spent nearly a decade outside Westminster and would need to rebuild relationships quickly in Parliament.

Despite those concerns, few figures in Labour possess his combination of experience, public recognition and electoral success. His victory in the Makerfield by-election returned him to the House of Commons and immediately intensified speculation about Starmer’s future.

Now, with Starmer stepping aside, that speculation appears close to becoming reality.

If Burnham secures the Labour leadership without a serious challenger, as many expect, he will become Britain’s next Prime Minister and inherit a government facing economic pressure, political division and a public increasingly impatient for change.

For a politician who has spent years waiting in the wings, the moment may finally have arrived.

 

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Former West Wales MS says Starmer resignation felt ‘increasingly inevitable’

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Samuel Kurtz says public frustration has grown after two years of Labour controversies and policy decisions

FORMER West Wales MS Samuel Kurtz has said Sir Keir Starmer’s resignation felt “increasingly inevitable” after months of controversy and public frustration.

The Welsh Conservative said he watched the Prime Minister’s Downing Street statement with “genuine frustration”, adding that he wanted the UK to be respected regardless of which party was in government.

Starmer announced on Monday (Jun 22) that he would resign as Prime Minister and Labour leader, just 12 days before the second anniversary of Labour’s 2024 general election victory.

Mr Kurtz said: “As a British citizen, I sighed genuine frustration while watching this morning. Whatever the political colour of the Government, I want our country to be respected at home and on the international stage.

Sam Kurtz

“But, in truth, this moment has felt increasingly inevitable as the weeks turned into months.”

He pointed to a series of controversies and policy decisions, including the Lord Alli gifts row, winter fuel allowance cuts, the Family Farm Tax, rising National Insurance, defence spending and domestic energy production.

Mr Kurtz said people “simply feel worse off”, adding that confidence in the economy remained low.

He said: “A Government should ultimately be judged on whether life is getting better for the people it serves.

“After two years marked by the controversies and a series of damaging policy decisions mentioned above, it’s difficult to argue this Government has passed that test.”

Mr Kurtz also questioned what would happen next, asking whether Labour would see an “Andy Burnham coronation”, whether Wes Streeting could build enough support, or whether an outsider could emerge.

He added that he would be watching the leadership contest “from the sidelines with interest”.

Labour is expected to open nominations for a new leader on July 9, with Starmer remaining in office until his successor is chosen.

 

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Haverfordwest lounge praised for charity work

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A HAVERFORDWEST venue has been praised for raising more than £2,600 for local charities through a series of community events.

Castle Ward county councillor Thomas Tudor visited The Waldo Lounge in Haverfordwest with Henry Tufnell MP, where they met manager Stephanie Davies.

Cllr Tudor said Stephanie had “truly embraced” her role in the community, organising events including a duck race, sports quiz, Mad Hatter’s tea party for Little Loungers, a bake sale and a drag night show.

Together, the events have raised £2,637 for local good causes.

Charities to benefit include The VC Gallery, Tŷ Hafan and Adam’s Bucketful of Hope Cancer Support Centre.

Cllr Tudor said: “It was lovely to introduce Henry Tufnell MP to Stephanie Davies, manager of The Waldo Lounge in Haverfordwest.

“Stephanie has truly embraced her role in the community of Haverfordwest, running many exciting initiatives and raising a staggering £2,637 for local charities.”

The fundraising continues this week, with Rock ’n’ Roll Bingo and a Wild West country and western night featuring a rodeo bull.

Caption: Community support: Thomas Tudor, Stephanie Davies and Henry Tufnell MP outside The Waldo Lounge in Haverfordwest.

 

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