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Cleft lip research may reduce childhood operations

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RESEARCH could help children born with a cleft lip and palate to avoid multiple operations as they grow up.

Around one in every 700 babies worldwide is born with a cleft lip or palate and reconstructive surgery is usually required during the early months.

As they grow and develop, some children may require additional surgery to improve facial appearance and function or the alignment of the jaw.

In a bid to reduce the need for multiple operations, computer scientists at Aberystwyth University are working with clinical experts to better forecast growth patterns in a baby’s mouth.

They are using 3D models and machine learning techniques to accurately predict what the outcomes of surgery will look like in five or ten years’ time.

Speaking during Cleft Lip and Palate Awareness Week 2025, lead investigator Professor Reyer Zwiggelaar from the Department of Computer Science at Aberystwyth University said:

“We want our research to lead to better outcome for patients born with a cleft lip or palate. Although corrective surgery for the majority of cleft lip or palate patients is successful, some require further intervention as they grow older. Using state-of-the-art deep learning technologies, we aim to provide surgeons with the tools they need to make precision-informed decisions before operating. We hope our work will help avoid the need for some children to go through additional operations.”

Cory Thomas, a research software engineer in the Department of Computer Science at Aberystwyth, said: “We are developing algorithms which will be able to identify six significant points in a baby’s mouth and these annotations can then be used to predict future growth. The software will help avoid what is referred to in clinical terms as “bad growth” which requires further surgical intervention, for example, to address a flattening of the face.”

The research at Aberystwyth is being informed by the expertise and experience of a clinical surgeon and an orthodontist who have been working with young cleft lip and palate patients for many years.

Bruce Richard, a retired plastic surgeon who specialised in cleft and palate surgeon at Birmingham Children’s Hospital for over 30 years, said:

“About 25% of children born with a complete cleft lip and palate end up with poor mid-face growth by the age of 16 and can choose to have a major bony operation to pull the mid face and the upper jaw teeth forward to correct the ‘caved in’ mid-face look.

“If we could predict which children are at the highest risk of experiencing this poor growth, then we could develop new strategies with dental appliances to try and reduce the issue before the child reaches 5-8 years of age. Success would mean fewer teenagers having to go through a major operation in young adulthood.”

Lars Enocson, lead Cleft Orthodontic Consultant at Birmingham Children’s Hospital, said: “The way the face grows in childhood depends on your genes and the world around you, like good food or pollution levels. If a child with a cleft lip and palate never has an operation to repair the cleft, then the face grows normally. Our study is looking at the shape of the baby’s upper jaw at birth to see if there is any particular 3-D shape that predicts those who get poor growth after surgery. Knowing this would allow choices about how we care for the child as they are growing.” 

The next stage of the research will focus on building 3D prediction models, and a series of clinical trials will be required before the technology can be used in a medical setting.

The research has received funding from the VTCT Foundation, a charity that funds research for people living with a visible difference, in addition to funding from Aberystwyth University.

Medical Imaging

The work on cleft lip or palate builds on years of medical imaging processing expertise in the Department of Computer Science at Aberystwyth University.

The technique allows for in-depth but non-invasive exploration of internal anatomy and has led to a significant number of healthcare developments, particularly for image analysis of breast and prostate cancer cases.

Other applications include using the software to examine Multiple Sclerosis lesions, stroke rehabilitation, and the diagnosis and management of endometriosis. 

 

Health

RCN Wales appoints Nicola Williams as Executive Director

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NICOLA WILLIAMS will take up the role in April, bringing more than three decades of experience in nursing and senior leadership.

The Royal College of Nursing (RCN) has announced the appointment of Nicola Williams as its new Executive Director for Wales.

She joins the organisation from Velindre University NHS Trust, where she currently serves as Executive Director for Nursing, Allied Health Professionals and Health Care Scientists. With 38 years of experience in nursing and more than six years at executive board level, she is widely recognised across NHS Wales for her work in improving patient outcomes.

A highly experienced strategic leader, Williams has worked across a wide range of clinical and organisational settings. She has led major transformation programmes, strengthened national clinical leadership networks and championed innovation and evidence-based improvements in care. Her work has contributed to changes adopted across Wales and has been recognised with national awards.

Speaking about her appointment, Nicola Williams said: “I feel privileged to be appointed as Executive Director of RCN Wales. I’m a proud nurse, passionate about patient safety and improving care standards.

“Delivering the best care is only possible when nursing staff are supported to work in safe, inclusive environments. I will stand alongside members and their patients.

“Nursing staff are the backbone of health and care. I am determined to support our members across Wales, wherever they work, to meet the challenges ahead and shape the future of our profession.

“I look forward to meeting members across Wales and ensuring our work is informed by their experiences and expertise.”

In her new role, Williams will lead the RCN’s work in Wales and provide strategic leadership across key priority areas spanning the UK.

She succeeds Helen Whyley, who has held the position since February 2019 and will move into a new role as Director of Service Innovation at the RCN.

 

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Health

Decision pending on adult mental health referral pathway

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HYWEL DDA University Health Board will decide next week whether to make changes to the GP referral pathway for routine adult mental health services permanent.

The decision will be taken at a public Board meeting on Thursday (Mar 26).

Board members will consider a proposal to formalise changes already introduced in Ceredigion and, if approved, roll out the revised pathway across Pembrokeshire and Carmarthenshire.

Since March 2025, adults in Ceredigion seeking routine mental health support have been advised by their GP to contact the NHS 111 Wales ‘Press 2’ service, rather than being referred directly to the county’s Community Mental Health Team.

The temporary change was introduced in response to ongoing staffing shortages. Health Board officials say the approach has helped maintain timely access to face-to-face assessments for those who need them, while directing initial contact through a single access point.

The 111 ‘Press 2’ service provides telephone assessments by local wellbeing practitioners, supervised by registered mental health nurses, offering advice, support and onward referrals where required.

At its November 2025 meeting, the Board agreed to extend the temporary pathway until the end of March 2026. A nine-week engagement exercise followed, running from December 8 to February 9, to gather feedback from patients, professionals and stakeholders on the potential long-term impact.

Andrew Carruthers, Chief Operating Officer at Hywel Dda University Health Board, said: “I would like to thank everyone who took the time to share their views and experiences.

“I would also like to thank West Wales Action for Mental Health for supporting engagement with patients, including those with lived experience, alongside GPs, primary care teams, mental health staff and third sector partners.

“Our priority is to ensure mental health services remain accessible, fair and sustainable. The temporary changes in Ceredigion have shown some positive benefits, and the feedback we have received from across the three counties will play an important role in shaping the Board’s decision.”

The Board will review all evidence and feedback before making a final decision on the future of the adult mental health referral pathway.

GPs will continue to refer patients with urgent or complex needs directly to community mental health teams where appropriate, and have access to a dedicated NHS 111 professional line for additional clinical advice.

Further details, including the full Board papers, are available here:
https://biphdd.gig.cymru/amdanom-ni/eich-bwrdd-iechyd/cyfarfodydd-y-bwrdd-2026/agenda-a-phapuraur-bwrdd-26-mawrth-2026/

The meeting will be streamed live from 9:30am on Thursday (Mar 26) via:
www.youtube.com/hywelddahealthboard1

 

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Health

Parents urged to check children’s vaccinations after meningitis cases

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Local pharmacy reports MenB vaccine shortage amid rising concern

PARENTS and carers across west Wales are being urged to check their children’s vaccination status following recent meningitis cases in the UK.

The warning comes as a local pharmacy has confirmed a shortage of the Meningitis B (MenB) vaccine, highlighting growing pressure on supplies.

Mendus Pharmacy said it currently has no availability of the vaccine due to what it described as a nationwide supply issue.

Mendus Pharmacy: No availability of the vaccine

In a statement, the pharmacy said: “We would like to inform our patients that, due to ongoing supply issues, we currently have no availability of the Meningitis B vaccine.

“Unfortunately, this is a nationwide shortage and all stock is currently unavailable.

“We understand this may be particularly concerning given the recent outbreak reported in Kent, and we completely appreciate the importance of timely vaccination.”

The pharmacy confirmed it is operating a waiting list and will contact patients once supplies return.

Health officials say keeping vaccinations up to date remains one of the most effective ways to prevent serious illness and reduce pressure on NHS services.

Dr Ardiana Gjini, Executive Director of Public Health at Hywel Dda University Health Board, urged parents to act.

She said: “Vaccination is one of the most effective ways we can protect children and young people from serious illness.

“Ensuring your child is fully vaccinated not only safeguards their health but also helps prevent the spread of infections within our communities.

“I strongly encourage all parents and carers to check their child’s vaccination status. If you are concerned that your child may have missed routine vaccinations, please speak to your GP.”

Meningococcal disease is a serious and potentially life-threatening infection that can lead to meningitis or septicaemia. While many people recover, some are left with long-term physical, neurological or psychological complications. Around one in ten cases can be fatal.

Although the disease can affect anyone, babies, young children, teenagers and young adults are at greatest risk.

In Wales, vaccines protecting against meningococcal strains A, B, C, W and Y are offered as part of the NHS immunisation programme. Infants receive the MenB vaccine, while teenagers are offered the MenACWY vaccine.

Latest figures from the Health Board show that uptake among 16-year-olds for the MenACWY vaccine stands at 76.4%, meaning a significant number of young people remain unprotected as they approach adulthood.

For younger children, uptake of the MenB vaccine is higher but still below the recommended 95% target. Around 92.8% of infants are vaccinated by their first birthday, rising slightly to 91.8% by their second.

Health officials say these figures reflect strong engagement from families and primary care teams but stress that continued vigilance is needed.

Families are being advised to check their child’s vaccination record with their GP or by contacting the Health Board directly. Parents should also ensure babies receive their scheduled MenB doses and that teenagers receive their MenACWY and 3-in-1 booster vaccines, which are currently being delivered in schools.

Parents are also urged to remain alert to the symptoms of meningitis and septicaemia and to seek urgent medical advice if they have concerns.

Further information on symptoms is available via NHS 111 Wales.

 

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