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Education

Swansea Uni to deliver advanced therapies

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A significant opportunity: University a centre for cell and gene therapies

SWANSEA U​NIVERSITY’S​ Medical School, through its partnership with Abertawe Bro Morgannwg University Health Board, is to be one of the centres to deliver advanced medical therapies to Wales, which is part of a major investment announced by Welsh Blood Services.

A recently formed health consortium, jointly led by the Welsh Blood Service (on behalf of NHS Wales) and the National Institute for Health Research Birmingham Biomedical Research Centre, has been awarded £7.3M of UK Government funding to ensure more patients benefit from a new generation of breakthrough therapies.

£1.5M will come directly to NHS Wales and £550K to Trakcel, a Welsh software company developing scheduling/tracking software for advanced therapies which is based upon technology developed at Swansea University.

The funding will support the Welsh Government’s commitment to developing an Advanced Therapies Strategy which will enable these therapies to be brought to Welsh patients and Advanced Therapy Medicinal Product (ATMP) companies to reach the clinical market, whilst building expertise, capability and capacity across NHS Wales to benefit patient outcomes.

Speaking of the award, Frank Atherton, Chief Medical Officer for Wales, said: “We welcome the announcement of the successful partnership between Birmingham, Nottingham and Wales NHS centres in bidding for Innovate UK monies. The project is aligned with our ambition to support the development, availability and adoption of new innovative therapies for patients in Wales. Cell- and gene-based advanced therapies offer exciting opportunities, not only for the way we treat people with previously incurable conditions, but also how we work together with industry and NHS Wales in bringing these treatments from bench to bedside.”

The NHS Wales role in the MW-ATTC consortium was led by the Welsh Blood Service, with support from Abertawe Bro Morgannwg and Cardiff & Vale University Health Boards along with the Life Sciences Hub Wales Special Interest Group on Cell and Gene Therapy, which brings together expertise from the Welsh NHS, Universities and industry in the Life Science sector.

As part of the contract award, one of the first advanced therapy treatment sites in Wales will be established within Abertawe Bro Morgannwg at the Joint Clinical Research Facility (JCRF) at Swansea University’s Medical School. The focus of the centre will be to develop the infrastructure, processes and skilled workforce required to enable patients to be cared for, from diagnosis through to post-treatment follow up.

Cath O’Brien, Director of the Welsh Blood Service and MW-ATTC Co-Director, said: “A significant opportunity exists to position Wales as a leader in clinical trial and routine delivery of cell and gene therapies to maximise Welsh patient benefit and opportunities for the national economy. The Welsh Government is committed to exploring these revolutionary developments in healthcare and we are excited to have worked alongside our consortium partners to secure funding through what was a highly competitive tendering process.”

One of the first products that will pass through the Welsh centres is that being developed by one of the consortium partners, Rexgenero and is intended to prevent the need for diabetes-related lower limb amputations for some no option patients. The incidence of diabetes is continuing to increase in Wales and already accounts for ~10% of the NHS Wales budget (£500M) with 200, 000 sufferers today rising to an estimated 500,000 by 2025. Currently around 2000 patients in Wales have non-healing lower limb ulcers that result in approximately 330 amputations per year.

The Midlands & Wales Advanced Therapy Treatment Centre (MW-ATTC) will identify barriers, challenges and solutions to facilitate future deployment and adoption of these transformative therapies within the UK healthcare system.

Advanced treatments, such as cell and gene therapies, show great promise for patients with chronic and terminal conditions that currently cannot be cured. Unlike conventional medicines, these new approaches often aim to selectively remove, repair, replace, regenerate and re-engineer a patient’s own genes, cells and tissues to restore normal function. The project will include potential treatments for arthritis, liver disease, several types of cancer, and diabetic ulcers.

Community

Cilgerran school could be discontinued as consultation launched

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A CONSULTATION on proposed changes for a north Pembrokeshire school, which attracted a near-400-strong petition in opposition to the council, has been launched.

At its May meeting, Pembrokeshire County Council considered a report of the School Modernisation Working Group which outlined the findings of a review of education provision in the Preseli area.

“In particular, the review considered the extent of surplus school places in the area, set against a significant decline in the pupil population,” the council in its consultation on proposals for discontinuation of Cilgerran Church in Wales Voluntary Controlled School has said.

A later July meeting of the council, following May’s agreed consultation with St David’s Diocese, backed a general consultation to discontinue Cilgerran Church in Wales Voluntary Controlled School, and to establish it as a 3-11 community school.

The consultation was launched on December 16 and runs to January 30.

Hundreds have opposed the proposed changes, with a petition, on the council’s own website opposing the changes recently closed after gaining 391 signatures.

Any petition of between 100 and 499 signatures triggers a debate at one of the council’s Overview and Scrutiny Committees, and any over 500 a debate at full council, meaning this petition will be heard by committee members at a later date.

The proposals for Cilgerran are part of a wide range of potential education changes in the county.

Two petitions, opposing the potential closures of Manorbier and Ysgol Clydau schools, were recently heard at full council and a further petition opposing the potential closure of Stepaside School has recently been launched.

The Cilgerran e-petition, created by Louise Williams, raised concerns including the school could become part of a federation, a loss of permanent head teacher on site, a shared head teacher would have to oversee several schools, loss of funding control and the ability to maintain the school’s current healthy and stable funding, and a loss of commitment to the church, in turn could impact on the school’s and pupils values, beliefs and cultural beliefs. 

It said: “Ysgol Cilgerran VC school has strong links with the Church community in Cilgerran and we believe this will have a negative impact on the children who attend the school, the community of Cilgerran and the links between the two.

“We are proud of our school ethos and values which are strengthened by our links with the church. The school has close and strong relationships with our Church in Wales federation governors one of which is also our safeguarding governor.

“Our Church Federation governors work closely with the school and are regular visitors to the school and the children. They provide vital support and guidance to the school and have a positive impact on the Children’s education. We believe these links will be weakened by this proposal to remove our VC status and we believe this is an un-necessary action.”

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Community

Pleas to save fire-ravaged Manorbier school site heard

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A PLEA for councillors to not act as “judge, jury and executioner” when the potential closure of fire-ravaged Manorbier is decided upon next year was heard at full council.

At the December meeting of Pembrokeshire County Council, members received a petition opposing the potential closure of Manorbier School.

Manorbier Church in Wales VC School and its adjoining schoolhouse was severely damaged by a fire on October 11, 2022, which broke out in the school roof space.

After that, a ‘school from school’ was set up in Jameston Village Hall.

It had been hoped the school would be rebuilt, but earlier this year members of Pembrokeshire County Council backed a report of the School Modernisation Working Group which, amongst other recommendations, included a statutory consultation on proposals to discontinue Manorbier Church in Wales Voluntary Controlled School.

The decision attracted strong local opposition, with more than 1,500 people signing a petition on the council’s own website calling for the school to be rebuilt, meaning it passed the threshold for a formal hearing by members of the council.

The formal consultation for the discontinuation of Manorbier closes in just a few days on December 19.

Manorbier community councillor Richard Hughes

However, many of the council’s figures, especially on the level of surplus places at the school, have been strongly disputed.

Speaking at the December meeting, Richard Hughes, of Manorbier Community Council, said the council consultation was “deeply flawed and unlawful,” the quoted capacity figures after the fire damaged the original building “null and void,” with a true surplus of some 21 per cent.

“The school is clearly thriving under less-than-ideal conditions, your report claims 59 per cent [surplus], it’s misleading and artificial.”

He said the council was acting as “judge, jury and executioner” in its “deeply flawed” consultation.

Cllr Phil Kidney

Local member Cllr Phil Kidney said the staff, parents and pupils had been “living this process for three years,” adding: “At worst light we were misled for three years, living under this shadow, it’s not fair.

“We’ve been promised all along ‘we will rebuild this school; no matter what we do we will have to spend on this school, we have to hand it back in [a useable] condition.

“How members of staff have worked under these conditions for three years is amazing, the service they are providing in that school is fantastic.”

He criticised the consultation wording, feeling it painted Manorbier in an unfair light, saying it was stacked heavily in favour of St Florence school in a submitted question heard later at the meeting.

“We do feel there’s a hidden agenda, nothing more than a boost for St Florence school; we were led to believe was all about the positives and the negatives for the school; we have lost the trust in the director of education, we still feel we’re not been listened to.”

He said it was important councillors, when a final vote on Manorbier’s future, expected in March, keep an open mind “not just going along with the narrative: ‘We can’t afford it, and the figures are going down’.”

He went on to say: “We want to get the right vote, the moral vote, and get the school rebuilt.”

Cllr Guy Woodham

Cabinet member for education Cllr Guy Woodham praised the work at the school following the fire, saying he intended to “set the facts out” when it came to a final decision.

Leader of the independent group Cllr Huw Murphy said: “It just doesn’t sit right with me to close a school that has burned to the ground. Yes, we will respect the decision in March, however we haven’t handled the decision well. We need to do what’s right, and we haven’t done what’s right for Manorbier.”

Members agreed to note receipt of the petition prior to the final report before council in 2026.

Later in the meeting, Cllr Woodham disputed Cllr Kidney’s submitted question claim, Cllr Kidney telling Cllr Woodham: “We’ve put a lot of trust and faith in you on this consultation to make sure it’s fair and transparent. St Florence was referenced more times than our school, for a consultation I think it’s misleading.”

Cllr Woodham responded: “I will do my utmost to give a balanced report when I bring it back to full council.”

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Community

Plea to save Tegryn Ysgol Clydau school heard by councillors

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A PLEA to not “pluck the heart out of a community” by closing a Pembrokeshire village school was heard by councillors just days after a consultation into its future was launched.

At the December meeting of Pembrokeshire County Council, members received a petition opposing the potential closure of Ysgol Clydau, Tegryn, which had generated 648 responses on the council’s own website, meaning it crossed the threshold to be heard at full council.

A council statement accompanying the launch of the consultation said: “At its meeting on May 8, Pembrokeshire County Council considered a report of the School Modernisation Working Group which outlined the findings of a review of education provision in the Preseli area.

“In particular the review considered the extent of surplus school places in the area, set against a significant decline in the pupil population.”

The Ysgol Clydau petition states: “We demand that Pembrokeshire County Council reconsider its decision to close Ysgol Clydau and instead prioritise the needs of our community by keeping the school open. We oppose the closure of Ysgol Clydau and call for full public scrutiny before any decision is made.

“We urge you to engage in a meaningful dialogue with the community, listen to our concerns, and work with us to find alternative solutions that support the needs of our children and families.”

Sarah Farnden

Speaking at the meeting on behalf of the petitioners, Sarah Farnden, in an emotive plea, said the school was “not just a school but a sanctuary, a nurturing environment,” which offered “warmth, belonging and safety”.

“A village without a school becomes a village without families, a village without families becomes a village without a future,” she told members, adding: “Ysgol Clydau is not in debt, it’s not overspent, we’ve done everything asked of us, so why are we being punished?

“There has been a school on this site for 145 years, if you close Ysgol Clydau you are not closing a building you are closing a heritage; we are not here to fight you, we are here to beg you.”

Cllr Iwan Ward

Local member Cllr Iwan Ward said: “The decision of Pembrokeshire County Council to release this consultation on the closure a few days before Christmas is extremely disappointing, a time of year families should be concentrating on being together, not a time to have to face the threat of losing the heart of our community.”

To applause from the gallery, he added: “It’s not a matter of numbers on a paper, it’s a moral matter; the school is much more than four walls, it’s a safe place for children to grow and a cornerstone of community spirit.

“Closing a school like this rips the heart out of rural life, to threaten a school that isn’t failing is an action I cannot, and am not willing to, take quietly.

“I will stand with the staff, the governors, and the children also.”

Members heard the consultation had been expected to launch back in September but had been delayed due to staffing issues; its 42-day period due to now end in late January.

Members agreed to note the petition ahead of the consultation end, recommendations on the school’s future expected to be decided in March.

The final word went to Sarah Farnden, who said: “We’re not asking for special treatment, we’re asking for fairness and compassion; do not pluck the heart out of the community.”

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