Health
New rapid TB diagnosis detector to be developed in west Wales
WELSH researchers have been awarded funding of almost £1.2 million to develop a new detector for tuberculosis in humans and animals that can report a result in one hour.
The technology will be simple enough to be operated by any healthcare worker or veterinarian. It will be more specific and more sensitive than existing methods as well as significantly quicker than other types of tests.
Supported by funding from UKRI, the project brings together experts in tuberculosis, veterinary medicine, microbiology, microwave and photonic engineering, to develop a new solution to this global health problem.
TB is a major cause of suffering and death in humans and animals worldwide and is the second leading infectious killer of humans after COVID-19. There are currently around 10 million recorded human TB infections per year, with a death rate of 1.8 million per year.
The lack of a rapid accurate diagnosis, particularly in poorer nations, often leads to misdiagnoses and ineffective treatment of TB patients.
Professor Glyn Hewinson, Sêr Cymru research chair in the Centre of Excellence for Bovine Tuberculosis at Aberystwyth University, said: “The impact of TB is devastating, so developing a rapid diagnosis method could be truly transformative. Eliminating the human TB epidemic by 2050 is a key UN Sustainable Development Goal, and the World Health Organization highlights the need for more effective rapid diagnostic tests as a critical step. We are looking forward to working with our colleagues in Cardiff to make advances in this important area of research.”
The high prevalence of TB in cattle in parts of the UK has a major effect on both the livelihoods and wellbeing of farmers. The surveillance, diagnostic testing, badger culling and vaccination costs the UK government alone a total of £100 million per year.
Professor Les Baillie, Professor of Microbiology at the School of Pharmacy and Pharmaceutical Sciences at Cardiff University, and co-lead on the project said:
“Tuberculosis is a particular problem for farmers in Wales who have seen bovine TB decimate herds across the country. Diagnosis of the early stages of infection is challenging due to the lack of rapid, accurate tests.
“To address this, we are working with colleagues from Aberystwyth University to advance the development of a real-time test capable to detecting the presence of the pathogen in clinical and environmental samples.”
Aberystwyth experts will lead on the development and evaluation of an optical device which will for the first time attempt to solve issues with sample impurities and sensitivities.
Professor Nigel Copner, Head of the Business School and Academic Lead for the Engineering Unit at Aberystwyth University said:
“PCR testing is the gold standard for detecting pathogens but requires special processing for high sensitivity. However, most detection methods struggle with sample impurities.
“Using techniques developed in Cardiff, the photonics team at Aberystwyth University has innovated a method that enables high sensitivity detection directly from on-site samples, without needing time-consuming purification. If successful, this technique could achieve near-PCR sensitivity at the point of sampling, potentially revolutionising pathogen pandemic management.”
Further investment in the project will allow the new technology to be reduced in both size and cost to create a simple, low-cost detector, which will have particular benefit for use in developing countries.
The platform can be easily adapted to detect most other pathogens, including SARS-CoV-2 and MRSA, and could become an important tool to help control the spread of future pandemics.
The project is being funded by the UKRI cross research council responsive mode (CRCRM) pilot scheme, which is supporting new and creative interdisciplinary ideas emerging from the UK’s research community. The project has been awarded £1,199,669 and is one of 36 projects being funded by the £32.4 million UKRI CRCRM scheme.
Health
Accidental poisoning deaths surge in Wales as elderly face growing risk
Nearly 200% rise in five years raises alarm among safety experts
ACCIDENTAL poisoning deaths in Wales have surged dramatically, with new safety data showing a sharp increase in fatalities and a growing risk to older people living at home.
Figures released by the Royal Society for the Prevention of Accidents (RoSPA) show 252 people in Wales died from accidental poisoning in 2024, compared with 85 deaths in 2019 – an increase of almost 200 per cent in just five years.
Safety experts say older people are particularly vulnerable. Those aged 65 and over are more than five times more likely to die from an accidental poisoning – excluding narcotics – than the general population.
Even when alcohol-related incidents are excluded, people in this age group remain more than four times as likely to die from accidental poisoning.
Across the UK the trend is also rising sharply. Official figures show 5,770 people died from accidental poisonings in 2024, a 63 per cent increase over the past decade.
Hospitals in England recorded 17,252 admissions linked to non-narcotic poisoning last year, including nearly 5,000 cases involving older adults, who were 55 per cent more likely to require emergency hospital care.
RoSPA warns that people living with dementia face particular dangers inside their own homes because the condition can affect memory, recognition and perception. Everyday household products such as cleaning sprays, laundry detergents and medicines can easily be mistaken for food or drink.
Rebecca Guy, Senior Policy Manager at RoSPA, said: “Families caring for vulnerable relatives can experience genuinely frightening moments. Turning away for just a few seconds and realising someone has swallowed a cleaning product is sadly something some people have experienced.
“These incidents are not freak accidents. They are predictable and preventable events, and our new guidance is designed to help people take simple steps to make their homes safer.”
The charity has released new home-safety guidance aimed at helping families reduce risks, including practical advice on safely storing medicines and household chemicals.
Paul Edwards, Chief Nursing Officer at Dementia UK, said brightly coloured packaging on cleaning products can create confusion for people living with dementia.
“Laundry and cleaning products are often easily accessible in our homes, and many have brightly coloured packaging which can cause confusion for people with dementia, who may mistake them for edible items,” he said.
“One of the challenges of supporting someone with dementia is balancing an individual’s independence with their safety. It is impossible to eliminate risk completely, but these guidelines offer simple steps people can take to reduce the chance of these accidents happening.”
Simon Wheeler, Senior Knowledge Officer at Alzheimer’s Society, said staying safe at home is a key concern for families affected by dementia.
“As dementia progresses, people may find it harder to tell the difference between something that’s safe to eat and something that isn’t,” he said.
“Storing cleaning products safely and out of sight can help reduce the risk of accidents.”
RoSPA is urging households to take simple precautions, including locking away cleaning products, keeping medicines securely stored, and ensuring hazardous substances remain in their original packaging.
Safety experts warn that without greater awareness, accidental poisonings could continue to rise as the population ages and more people live independently at home.
Business
Crymych golf simulator, play space and wellness centre call
A CALL for approval for the use of Crymych industrial units as a golf simulator, child’s play space and a wellness centre offering a sauna, ice baths, and oxygen therapy has been submitted to county planners.
In an application to Pembrokeshire County Council, Mr and Mrs Evans, through agent Preseli Planning Ltd, seek a partly retrospective permission for the erection of commercial building containing three individual business units, at a former vacant storage yard at Parc Gwynfryn, Crymych.
A supporting statement says: “The building provides three sperate business spaces, two of the units are occupied, one as a golf simulator (7B 2) a second is occupied by a child’s role play and play space (7B 4) and the central unit (7B 3) is currently unoccupied, proposed to be let as a wellness centre.”
The site owners and applicants, Mr and Mrs Evans, are also the operators of the golf simulator enterprise and the original developers of the industrial estate, the statement says.
“The aim of the application is to regularise the existing building and existing and proposed uses. The building was substantially complete May 2025 and first occupied June 2025. Unit 7B2 is occupied by a golf simulator whereby users book slots online and self-serve.
“Unit 7B3 is currently unoccupied but would be occupied by wellness centre once planning permission is granted, consisting of sauna, ice baths, cryotherapy room, oxygen therapy etc. Unit 7B4 is occupied by a new enterprise which offers indoor roleplay space for children, Byd Bach.”
It adds: “In terms of the golf simulator, this is owner managed and the sites proximity to their main office within the site makes managing and attending the unit convenient and enables multiple businesses to be managed by the same members of staff.
“In terms of Byd Bach, this is operated by a local couple who also manage other premises in Crymych, amongst other employment. The site’s proximity to Crymych is therefore important and these arrangements are only successful given that the site is well-related to Crymych.
“The offering would not disrupt existing comparable provision, the closest facility of this kind being in St Clears, well beyond the catchment of this facility.
“The third unit is not yet occupied but would be operated by a local spinal injury sufferer, and athlete, who would benefit from the facilities themselves and offer therapy for others.”
Citing a recently-approved change on use of a building on the industrial site itself to a Hair and Beauty Salon, it said it was considered the development would not have a significant detrimental effect on the overall supply of business units or land in Pembrokeshire or Crymych.
The application will be considered by county planners at a later date.
Community
Emergency call to protect Withybush Hospital by local councillors
AN EMERGENCY call for Pembrokeshire’s council to take greater action in safeguarding the future of Withybush hospital is to be heard next week.
At the full council meeting of March 5, an emergency notice of motion by the council’s 11-strong Conservative Party group will demand that the Welsh Government immediately reverses the decision to cease emergency general surgery at Withybush Hospital.
Last year, Hywel Dda University Health Board consulted with its communities on options for change in critical care, dermatology, emergency general surgery, endoscopy, ophthalmology, orthopaedics, stroke, radiology and urology.
It said its Clinical Services Plan focuses on nine healthcare services that are “fragile and in need of change”.
The proposed changes included an option for Withybush patients needing specialist critical care being transferred to Glangwili.
At a recent two-day meeting, the board, amongst its many other decisions, backed changes into emergency general surgery which will see no emergency general surgery operations taking place at Withybush, but a strengthening of the same-day emergency care (SDEC).
A petition against the plans already has more than 4,000 signatures and has met an angry response from local politicians and campaigners.
At the March council meeting, the Conservative council group, led by Cllr Di Clements, will say: “The Welsh Government has powers of intervention in Sections 26-28 of the NHS (Wales Act) 2006 which enables it to intervene in decisions made by a health board, in this case the Hywel Dda University Health Board.”
It says that Pembrokeshire residents “have seen continual downgrading of services over the years, and this has been detrimental to all residents,” adding: “We believe this recent decision is life threatening to those who need emergency surgery and a matter of resident’s safety.
“Every hour lost, on average, survival rates decrease by four per cent. Those who live furthest west and north will be affected the most.”
The group adds: “We are concerned especially that this has the huge potential to affect A&E provision. With limited opportunity for doctors to operate we are concerned that our county hospital will be left with few or no senior surgeons and A&E will be forced to close.”
The group has also questioned the accuracy of figures quoted by the First Minister Eluned Morgan on the number of affected patients, saying: “HDUHB own figures for the changes to emergency surgery put the number at nine per week, not five.”
The group has said it “acknowledges that Pembrokeshire County Council has no control over health services in the county, but the 60 county councillors represent approximately 120,000 people who at some point may need hospital services”.
Group leader Cllr Di Clements said: “I am certain the whole county will support our aim to prevent any more downgrading of services at Withybush.
“We are treated like second class citizens, and it is just not good enough.”
-
News7 days agoHoax 999 call sparks massive lifeboat and helicopter rescue — man arrested
-
Crime7 days agoWest Wales man jailed for murder of five-month-old baby
-
Charity7 days agoBig Bash brings community together to support grieving children
-
Health7 days agoPetition against hospital service changes surges past 6,000 signatures
-
Health7 days agoWho is responsible for NHS changes affecting west Wales?
-
Crime7 days agoSt Dogmaels man jailed over hundreds of indecent images
-
Sport7 days agoWRU facing vote of no confidence as clubs force extraordinary meeting
-
Crime6 days agoMan given suspended sentence after assault and damage offences









